Yuhri Miyawaki, M.Sc., Atsuo Suzuki, M.Sc., Junko Fujita, B.Sc., Asuka Maki, B.Sc., Eriko Okuyama, B.Sc., Moe Murata, B.Sc., Akira Takagi, Ph.D., Takashi Murate, M.D., Ph.D., Shinji Kunishima, Ph.D., Michio Sakai, M.D., Kohji Okamoto, M.D., Ph.D., Tadashi Matsushita, M.D., Ph.D., Tomoki Naoe, M.D., Ph.D., Hidehiko Saito, M.D., Ph.D., and Tetsuhito Kojima, M.D., Ph.D.: Brief Record: Thrombosis from a Prothrombin Mutation Conveying Antithrombin Resistance Patients with hereditary thrombophilia often present with unusual clinical episodes of venous thrombosis in a young age group and recurrence in atypical vessels, with a family history of the condition often.1 Genetic research of hereditary thrombophilia have revealed two types of genetic defects: loss-of-function mutations in the natural anticoagulants antithrombin, proteins C, and proteins S, along with gain-of-function mutations in procoagulant factors V and II .2 To date, numerous genetic defects have been found in families with hereditary thrombophilia, but there could be many undiscovered causative mutations.3 Here, we explain a case of hereditary thrombosis induced by a novel system of antithrombin resistance, a gain-of-function mutation in the gene encoding the clotting aspect prothrombin .In the study, experts analyzed data gathered by the annual American Time Use Survey between 2005 and 2013. The survey, executed by the Bureau of Labor Statistics, measures the amount of time people spend at numerous activities. The analysis authors then compared the time estimates with data on time spent with your physician collected from 2006 to 2010 by the National Ambulatory HEALTH CARE Survey. Whites only had to cool their heels for approximately 80 minutes normally in a doctor’s waiting room. By comparison, blacks had to hold back an average 99 minutes, and Hispanic wait times averaged around 105 a few minutes, the study found.